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IGF-1R(DMC721) IgG1 Chimeric mAb

Anti-IGF-1R antibody(DMC721) IgG1 Chimeric Monoclonal Antibody
5/5

货号:28289

规格: 100 µg

库存状态:In Stock

           产品描述          
货号:   28563
产品全名:   IGF-1R(DMC721) IgG1 Chimeric 单抗
基因符号   CD221; IGFIR; IGFR; JTK13
描述:   IGF-1R antibody(DMC721) IgG1 Chimeric 单抗
背景:   This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
经过测试的应用:   Flow Cyt
推荐稀释比:   Flow Cyt 1/100
种属反应性:   Rabbit
亚型:   Rabbit/Human Fc chimeric IgG1
纯化:   Purified from cell culture supernatant by affinity chromatography
种属反应性:   人 IGF-1R
成分:   Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. IGF-1R protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-IGF-1R (DMC721) mAb on Expi293 cells transfected with human IGF-1R (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).
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