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Human TSHR Full Length Protein

Human TSHR Full Length Protein-Synthetic Nanodisc
5/5

$4,400.00

Cat.#:  11026

   Size:   50 μg

In Stock

          Product Description          
Cat.#:     11026
Product Name:   Human TSHR Full Length Protein
规格:    10 µg, 50 µg and 100 µg
Synonyms:   CHNG1; hTSHR-I; LGR3
Target:    TSHR
UNIPROT ID:    P16473
描述:    Human TSHR full length protein-synthetic nanodisc
背景:     The protein is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism.
Species/Host:    HEK293
Molecular Weight:    The human full length TSHR protein has a MW of 86.8 kDa
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure1. Elisa plates were pre-coated with Flag Tag TSHR-Nanodisc (0.2 µg/per well). Serial diluted Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for Flag monoclonal antibody binding with TSHR-Nanodisc is 2.108ng/ml.

Figure2. Human TSHR-Nanodisc, Flag Tag on SDS-PAGE
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