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Human LGR5 Full Length Protein

Human LGR5 Full Length Protein-Synthetic Nanodisc
5/5

¥38,200.00

Cat.#:  11054

   Size:   50 μg

In Stock

          Product Description          
目录:     11054
产品名称:   Human LGR5 Full Length Protein
规格:    10 µg, 50 µg and 100 µg
基因符号:   FEX; GPR49; GPR67; GRP49; HG38
Target:    LGR5
UNIPROT ID:    O75473
描述:    Human LGR5 full length protein-synthetic nanodisc
背景:     The protein is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.
Species/Host:    HEK293
Molecular Weight:    The human full length LGR5 protein has a MW of 100.0 kDa
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure1. Elisa plates were pre-coated with Flag Tag LGR5-Nanodisc (0.2 µg/per well). Serial diluted Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for Flag monoclonal antibody binding with LGR5-Nanodisc is 5.199ng/ml.

Figure2. Human LGR5-Nanodisc, Flag Tag on SDS-PAGE
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