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IL5RA (DMC393) IgG1 Chimeric mAb

Anti-IL5RA (DMC393) IgG1 Chimeric Monoclonal Antibody
5/5

¥445.00

货号:28211

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   28211
产品全名:   IL5RA(DMC393) IgG1 Chimeric 单抗
基因符号   IL5Ra;CD125;IL-5 R alpha
描述:   IL5RA antibody(DMC393) IgG1 Chimeric 单抗
背景:   The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3); colony stimulating factor 2 (CSF2:GM-CSF); and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding; and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin); which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.
经过测试的应用:   Flow Cyt
推荐稀释比:   Flow Cyt 1:100
种属反应性:   Rabbit
亚型:   Rabbit:Human Fc chimeric IgG1
纯化:   Purified from cell culture supernatant by affinity chromatography
种属反应性:   人 IL5RA
成分:   Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-IL5RA (DMC393) on Expi293 cells transfected with human IL5RA (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
           引用文献