| 货号: 11123 |
| 产品全名: 人 CAV1 Full Length 蛋白 |
| 规格: 10/50/100 µg |
| 基因符号 BSCL3; CGL3; LCCNS; MSTP085; PPH3; VIP21 |
| 目标蛋白: CAV1 |
| UNIPROT ID: Q03135 |
| 描述: 人 CAV1 full length protein-synthetic nanodisc |
| 背景: The scaffolding protein is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1. |
| 物种/宿主: HEK293 |
| 分子量: The human full length CAV1 protein has a MW of 20.3 kDa |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| 储存和运输: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure1. Elisa plates were pre-coated with Flag Tag CAV1-Nanodisc (0.2 µg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with CAV1-Nanodisc is 4.671ng/ml. | 
Figure2. Human CAV1-Nanodisc, Flag Tag on SDS-PAGE |
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