| 货号: 11559 |
| 产品全名: 人 ADAMTS1 蛋白 |
| 规格: 10/50/100 µg |
| 基因符号 ADAM-TS 1;ADAM-TS1;ADAMTS-1;METH-1 |
| 目标蛋白: ADAMTS1 |
| UNIPROT ID: Q9UHI8 |
| 描述: Recombinant human ADAMTS1 Protein with C-terminal 6xHis tag |
| 背景: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function. [provided by RefSeq, Jul 2008] |
| 物种/宿主: HEK293 |
| 分子量: The protein has a predicted molecular mass of 101.1 kDa after removal of the signal peptide. The apparent molecular mass of ADAMTS1-His is approximately 100-130 kDa due to glycosylation. |
| 分子特征: ADAMTS1(Leu50-Ser967) 6×His tag |
| 纯化: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| 储存和运输: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Human ADAMTS1 Protein, His Tag on SDS-PAGE under reducing condition. |
