武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

邮箱:info@neweastwuhan.com

咨询:027 – 63497286 

TIGIT (DM178) Rabbit mAb

Anti-TIGIT (DM178) Rabbit Monoclonal Antibody
5/5

¥445.00

货号:28521

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   28521
产品全名:   TIGIT(DM178) 兔单克隆抗体
基因符号   TIGIT;VSIG9;VSTM3
描述:   TIGIT antibody(DM178) 兔单克隆抗体
背景:   This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.
经过测试的应用:   ELISA; Flow Cyt
推荐稀释比:   ELISA 1:5000-10000; Flow Cyt 1:100
种属反应性:   Rabbit
亚型:   Rabbit IgG
纯化:   Purified from cell culture supernatant by affinity chromatography
种属反应性:   人 TIGIT
成分:   Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-TIGIT (DM178) on Expi293 cells transfected with human TIGIT (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

Figure 2. Competition assay demonstrating DM178 blockade of CD155 binding to Jurkat cell line transfected with human TIGIT,and competitive activity is better than etigilimab biosimilar.
           引用文献