武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处
武汉费斯德生物科技有限公司是美国NewEast Biosciences在中国的办事处。NewEast Biosciences 在十二年前率先研发俩种独特的抗体。这俩种抗体仅仅识别活性的GTP酶或者突变的Oncogene。 GTP酶涉及(1)响应细胞表面受体激活的信号转导,包括跨膜受体,例如介导味觉、嗅觉和视觉的那些,(2)核糖体的蛋白质生物合成,(3)调节细胞分化、增殖、分裂和运动,(4)蛋白质通过膜的易位,(5)细胞内囊泡的运输,以及囊泡介导的分泌和摄取,通过GTP酶控制囊泡外壳组装。Oncogene侧是诱发癌症的基因。
我公司将向你提供以下的独一无二的三种抗体或者试剂盒: (1) 仅识别 GTP酶的活性构型的产品, 它可以让你能够量化GTP酶在细胞中的活性和分布。(2) 识别突变 Oncogene蛋白, 但不认识相应野生型的抗体。 (3) 对 cAMP 和 cGMP 具有超亲和力(无需乙酰化)ELISA检测试剂盒。这些产品被将近一千篇同行评议的文章所引用。
¥2,800.00
产品名称: Rac3 小鼠单抗 |
货号: 26064 |
基因符号: RAC3 |
描述: Rac3 小鼠单抗 |
背景: Rac3 is a small GTPase of the Rho family that relays signals through direct interaction of GTP-bound Rac3 with downstream effector molecules. The Rac subfamily consists of Rac1, Rac2, and Rac3 proteins. While Rac1 is ubiquitously expressed, Rac2 and Rac3 are largely restricted to hematopoietic and neural tissues, respectively. Rac3 has biochemical properties that are closely related to Rac1. Both Rac1 and Rac3 have been implicated in the regulation of cell migration and invasion in human metastatic cancer. |
免疫原 : A synthetic peptide near the C-terminus of human Rac3. |
经过测试的应用: ELISA, WB, IHC, IP |
推荐稀释比: ELISA: 1:1000-1:5000 WB: 1:100-1:1000 IHC: 1:50-1:100 |
Concentration: 1 mg/ml |
种属反应性: Mouse |
形式: Liquid |
克隆性: Monoclonal |
亚型: IgG |
纯化: Purified from ascites |
成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
种属反应性: Specifically recognizes Rac3, but not Rac1 or Rac2 of vertebrates. |
储存条件: Store at -20°C. Avoid repeated freezing and thawing |
蛋白质印迹:
Western blot analysis of recombinant Rac3 proteins. Purified his-tagged Rac1 (货号: 10101), Rac2 (货号: 10184), and Rac3 (货号: 10182) proteins were blotted with anti-Rac3 monoclonal antibody (货号: 26064).