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Nectin4 (DMC438) IgG1 Chimeric mAb

Anti-Nectin4 (DMC438) IgG1 Chimeric Monoclonal Antibody
5/5

¥445.00

货号:28226

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   28226
产品全名:   Nectin4(DMC438) IgG1 Chimeric 单抗
基因符号   EDSS1; LNIR; nectin-4; PRR4; PVRL4
描述:   Nectin4 antibody(DMC438) IgG1 Chimeric 单抗
背景:   This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17:TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1; an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.
经过测试的应用:   Flow Cyt
推荐稀释比:   Flow Cyt 1:100
种属反应性:   Rabbit
亚型:   Rabbit:Human Fc chimeric IgG1
纯化:   Purified from cell culture supernatant by affinity chromatography
种属反应性:   人 NECTIN4
成分:   Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-Nectin4 (DMC438) on Expi293 cells transfected with human Nectin4 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
           引用文献