武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处
武汉费斯德生物科技有限公司是美国NewEast Biosciences在中国的办事处。NewEast Biosciences 在十二年前率先研发俩种独特的抗体。这俩种抗体仅仅识别活性的GTP酶或者突变的Oncogene。 GTP酶涉及(1)响应细胞表面受体激活的信号转导,包括跨膜受体,例如介导味觉、嗅觉和视觉的那些,(2)核糖体的蛋白质生物合成,(3)调节细胞分化、增殖、分裂和运动,(4)蛋白质通过膜的易位,(5)细胞内囊泡的运输,以及囊泡介导的分泌和摄取,通过GTP酶控制囊泡外壳组装。Oncogene侧是诱发癌症的基因。
我公司将向你提供以下的独一无二的三种抗体或者试剂盒: (1) 仅识别 GTP酶的活性构型的产品, 它可以让你能够量化GTP酶在细胞中的活性和分布。(2) 识别突变 Oncogene蛋白, 但不认识相应野生型的抗体。 (3) 对 cAMP 和 cGMP 具有超亲和力(无需乙酰化)ELISA检测试剂盒。这些产品被将近一千篇同行评议的文章所引用。
¥389.00
货号: 12220 |
产品全名: Mouse CDH17 蛋白 |
规格: 10/50/100 µg |
基因符号 HPT-1;HPT-1/LI |
目标蛋白: CDH17 |
UNIPROT ID: Q9R100 |
描述: Recombinant mouse CDH17 protein with C-terminal 6xHis tag |
背景: Enables proton-dependent oligopeptide secondary active transmembrane transporter activity. Involved in germinal center B cell differentiation; marginal zone B cell differentiation; and spleen development. Acts upstream of or within calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; homophilic cell adhesion via plasma membrane adhesion molecules; and oligopeptide transport. Located in cell surface and plasma membrane. Is expressed in several structures, including common bile duct; gut; spleen; trunk; and urogenital sinus. Orthologous to human CDH17 (cadherin 17). [provided by Alliance of Genome Resources, Apr 2022] |
物种/宿主: HEK293 |
分子量: The protein has a predicted molecular mass of 85.1 kDa after removal of the signal peptide. The apparent molecular mass of mCDH17-His is approximately 70-130 kDa due to glycosylation. |
分子特征: Mouse CDH17(Phe26-Met786) 6×His tag |
纯化: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
储存和运输: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Mouse CDH17 Protein, His Tag on SDS-PAGE under reducing condition. |