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Human P2RX7 Protein, hFc Tag

Recombinant human P2RX7 protein with N-terminal human Fc tag
5/5

¥479.00

货号:11265

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11265
产品全名:   人 P2RX7 蛋白
规格:   10/50/100 µg
基因符号   P2X7
目标蛋白:    P2RX7
UNIPROT ID:    Q99572
描述:   Recombinant human P2RX7 protein with N-terminal human Fc tag
背景:     The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 59.2 kDa after removal of the signal peptide. The apparent molecular mass of hFc-P2RX7 is approximately 55-70 kDa due to glycosylation.
分子特征:   hFc(Glu99-Ala330) P2RX7(Ser47-Val334)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human P2RX7 Protein, hFc Tag on SDS-PAGE under reducing condition.
           引用文献