| 货号: 11629 |
| 产品全名: 人 NKG2A 蛋白 |
| 规格: 10/50/100 µg |
| 基因符号 CD159A;NKG2;NKG2A |
| 目标蛋白: NKG2A |
| UNIPROT ID: P26715 |
| 描述: Recombinant Human NKG2A Protein with N-terminal human Fc tag |
| 背景: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jan 2015] |
| 物种/宿主: HEK293 |
| 分子量: The protein has a predicted molecular mass of 42.2 kDa after removal of the signal peptide.The apparent molecular mass of hFc-NKG2A is approximately 35-55 kDa due to glycosylation. |
| 分子特征: hFc(Glu99-Ala330) NKG2A(Pro94-Leu233) |
| 纯化: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| 储存和运输: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Human NKG2A Protein, hFc Tag on SDS-PAGE under reducing condition. |
