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Human MMP11 Protein, hFc Tag

Recombinant human MMP11 protein with C-terminal human Fc tag
5/5

¥479.00

货号:11703

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11703
产品全名:   人 MMP11 蛋白
规格:   10/50/100 µg
基因符号   MMP-11;SL-3;ST3;STMY3
目标蛋白:    MMP11
UNIPROT ID:    P24347
描述:   Recombinant human MMP11 protein with C-terminal human Fc tag
背景:     Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 76.5 kDa after removal of the signal peptide.The apparent molecular mass of MMP11-hFc is approximately 70-100 kDa due to glycosylation.
分子特征:   MMP11(Arg32-Leu488) hFc(Glu99-Ala330)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human MMP11 Protein, hFc Tag on SDS-PAGE under reducing condition.
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