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Human FGFa (154AA) Protein

Recombinant Human Fibroblast Growth Factor 1/Fibroblast Growth Factor Acidic is produced by our E.coli expression system and the target gene encoding Ala2-Asp155 is expressed.
5/5

¥365.00

货号:12085

规格: 50 μg

库存状态:In Stock

           产品描述          
货号:   12085
产品全名:   人 FGFa (154AA) 蛋白
规格:   10/50/100 µg
基因符号   Fibroblast Growth Factor 1;FGF-1;Acidic Fibroblast Growth Factor;aFGF;Endothelial Cell Growth Factor;ECGFHeparin-Binding Growth Factor 1;HBGF-1;FGF1;FGFA
目标蛋白:    FGFa
UNIPROT ID:    P05230
描述:   Recombinant Human Fibroblast Growth Factor 1/Fibroblast Growth Factor Acidic is produced by our E.coli expression system and the target gene encoding Ala2-Asp155 is expressed.
背景:     FGF acidic, also known as ECGF, FGF-1and HBGF-1, is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. It is a mitogenic peptide that is produced by multiple cell types and stimulates the proliferation of cells of mesodermal, ectodermal, and endodermal origin. Its association with heparan sulfate is a prerequisite for activation of FGF receptors. Internalized FGF acidic migrates to the nucleus where it is phosphorylated by nuclear PKC delta, exported to the cytosol, dephosphorylated, and degraded. Intracellular FGF acidic inhibits p53 activity and proapoptotic signaling.
物种/宿主:    E.coli
分子量:   17.3 KDa
分子特征:   Not available
纯化:   Greater than 95% as determined by reducing SDS-PAGE.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Greater than 95% as determined by reducing SDS-PAGE.
           引用文献