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Human CLDN4(145-157) Protein, hFc Tag

Recombinant Human CLDN4(145-157) Protein with C-terminal human Fc tag
5/5

¥389.00

货号:11844

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11844
产品全名:   人 CLDN4(145-157) 蛋白
规格:   10/50/100 µg
基因符号   CPE-R;CPER;CPETR;CPETR1;hCPE-R;WBSCR8
目标蛋白:    CLDN4
UNIPROT ID:    O14493
描述:   Recombinant Human CLDN4(145-157) Protein with C-terminal human Fc tag
背景:     The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq, Sep 2013]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 27.6 kDa after removal of the signal peptide. The apparent molecular mass of CLDN4(145-157)-hFc is approximately 25-35 kDa due to glycosylation.
分子特征:   CLDN4(Gln145-Lys157) hFc(Glu99-Ala330)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human CLDN4(145-157) Protein, hFc Tag on SDS-PAGE under reducing condition.
           引用文献