| 货号: 11194 |
| 产品全名: 人 CEACAM5 蛋白 |
| 规格: 10/50/100 µg |
| 基因符号 CEACAM-5;D66e;EA;econium antigen 100 |
| 目标蛋白: CEACAM5 |
| UNIPROT ID: P06731 |
| 描述: Recombinant human CEACAM5 protein with C-terminal 6xHis tag |
| 背景: This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. |
| 物种/宿主: HEK293 |
| 分子量: The protein has a predicted molecular mass of 72.2 kDa after removal of the signal peptide. The apparent molecular mass of CEACAM5-His is approximately 100-130 kDa due to glycosylation. |
| 分子特征: CEACAM5(Lys35-Ala685) 6×His tag |
| 纯化: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| 储存和运输: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Human CEACAM5 Protein, His Tag on SDS-PAGE under reducing condition. | 
Figure 2. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human CEACAM5, His tagged protein (11194) can bind Anti-CEACAM5 Antibody 28044 in a linear range of 2.56-320 ng/ml. |
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