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Human CD4 Protein, hFc Tag

Recombinant human CD4 protein with C-terminal human Fc tag
5/5

¥415.00

货号:11636

规格: 100 μg

库存状态:Under development

           产品描述          
货号:   11636
产品全名:   人 CD4 蛋白
规格:   10/50/100 µg
基因符号   CD4;D4mut;EU3
目标蛋白:    CD4
UNIPROT ID:    P01730
描述:   Recombinant human CD4 protein with C-terminal human Fc tag
背景:     This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 65.67 kDa after removal of the signal peptide.
分子特征:   CD4(Lys26-Trp390) hFc(Glu99-Ala330)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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