Human CD3D Protein, His Tag

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Recombinant human CD3D protein with C-terminal 6XHis tag

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¥3,600.00

Cat.#: 11586

Size: 100 μg

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目录: 11586

产品名称: Human CD3D Protein

规格: 10 µg, 50 µg and 100 µg

基因符号: T-cell surface glycoprotein CD3 delta chain;-cell receptor T3 delta chain

Target: CD3D

UNIPROT ID: P04234

描述: Recombinant human CD3D protein with C-terminal 6xHis tag

背景: The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009]

Species/Host: HEK293

Molecular Weight: The protein has a predicted molecular mass of 10.4 kDa after removal of the signal peptide. The apparent molecular mass of CD3D-His is approximately 15-25 kDa due to glycosylation.

Molecular Characterization: CD3D(Phe22-Ala105) 6×His tag

纯化:: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

储存和运输: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human CD3D Protein, His Tag on SDS-PAGE under reducing condition.

Arf6	Arl1	Arl3	Cdc42	Gα₁₂	Gα₁₃	Gα₁₄	Gα_i	Gα_o	Gα_q
Gα_s	Gα_z	Rab11	Rab12	Rab14	Rab17	Rab18	Rab25	Rab26	Rab28
Rab2A	Rab3	Rab30	Rab31	Rab35	Rab38	Rab39	Rab41	Rab4A	Rab5
Rab7	Rab8A	Rab9A	Ral	Rac1	Ran	Rap1	Ras	Rheb	RhoA	Sar1

Albumin	Apolipoprotein	BAG1	BMP3	Cystatin	EYA2
FASCIN	GAPDH	GRB7	KIM1	MUC1	ORAIL
RAC-8A	SEPTIN9	SLC7A5	SUMO	Survivin	TFF3
Vimentin	Transferrin	β-Actin	β-Tubulin

ABL	AKT	ALK	ATM	ß-CATENIN	BRAF	BRCA1
BRCA2	CTCF	CTNNB1	EGFR	ERBB2	FBXW7	FGFR1
GNAQ	HRAS	IDH	JAK2	KIT	MEK1	NFE2L2
NOTCH1	PIK3CA	PTEN	RAS	RET	RHEB	SMAD4
SMO	STK11	TP53

Rab5 -GTP IF, IHC and IP	Rap1-GTP IF, IHC and IP
Ral-GTP IF, IHC and IP	Ran-GTP IF, IHC and IP
Sar1-GTP IF, IHC and IP	Arf6-GTP IF, IHC and IP
Rab11-GTP IF, IHC and IP

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