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Human ACVRL1 Protein, hFc Tag

Recombinant Human ACVRL1 Protein with C-terminal human Fc tag
5/5

¥3,400.00

Cat.#:  11893

   Size:   100 μg

In Stock

          Product Description          
目录:     11893
产品名称:   Human ACVRL1 Protein
规格:    10 µg, 50 µg and 100 µg
基因符号:   ACVRLK1;ALK-1;ALK1;HHT;HHT2;ORW2;SKR3;TSR-I
Target:    ACVRL1
UNIPROT ID:    P37023
描述:    Recombinant Human ACVRL1 Protein with C-terminal human Fc tag
背景:     This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq, Jul 2008]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 36.8 kDa after removal of the signal peptide. The apparent molecular mass of ACVRL1-hFc is approximately 35-70 kDa due to glycosylation.
Molecular Characterization:    ACVRL1(Asp22-Gln118) hFc(Glu99-Ala330)
纯化::    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1.Human ACVRL1 Protein, hFc Tag on SDS-PAGE under reducing condition.
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