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Human HRH3 Full Length Protein

Human HRH3 Full Length Protein-Synthetic Nanodisc
5/5

¥38,200.00

Cat.#:  11114

   Size:   50 μg

In Stock

          Product Description          
目录:     11114
产品名称:   Human HRH3 Full Length Protein
规格:    10 µg; 50 µg and 100 µg
基因符号:   GPCR97; HH3R
Target:    HRH3
UNIPROT ID:    Q9Y5N1
描述:    Human HRH3 Full Length Protein-Synthetic Nanodisc
背景:     Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system.
Species/Host:    HEK293
Molecular Weight:    The human full length HRH3 protein has a MW of 48.7 kDa
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Protein Families:    Druggable Genome, Transmembrane
Protein Pathways:    Neuroactive ligand-receptor interaction

Figure 1. Elisa plates were pre-coated with Flag Tag HRH3-Nanodisc (0.2μg/per well). Serial diluted Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for Flag monoclonal antibody binding with HRH3-Nanodisc is 2.708ng/ml.

Figure 2. Human HRH3-Nanodisc, Flag Tag on SDS-PAGE
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