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GDF15 (DMC474) IgG1 Chimeric mAb

Anti-GDF15 (DMC474) IgG1 Chimeric Monoclonal Antibody
5/5

¥445.00

货号:28250

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   28250
产品全名:   GDF15(DMC474) IgG1 Chimeric 单抗
基因符号   GDF-15; MIC-1; MIC1; NAG-1; PDF; PLAB; PTGFB
描述:   GDF15 antibody(DMC474) IgG1 Chimeric 单抗
背景:   This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types; acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia; inflammation; acute injury and oxidative stress. [provided by RefSeq; Aug 2016]
经过测试的应用:   Flow Cyt
推荐稀释比:   Flow Cyt 1:100
种属反应性:   Rabbit
亚型:   Rabbit:Human Fc chimeric IgG1
纯化:   Purified from cell culture supernatant by affinity chromatography
种属反应性:   人 GDF15
成分:   Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-GDF15 (DMC474) on Expi293 cells transfected with human GDF15 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
           引用文献