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Human FZD4 Full Length Protein

Human FZD4 Full Length Protein-Synthetic Nanodisc
5/5

¥38,200.00

Cat.#:  11120

   Size:   50 μg

In Stock

          Product Description          
目录:     11120
产品名称:   Human FZD4 Full Length Protein
规格:    10 µg, 50 µg and 100 µg
基因符号:   CD344; EVR1; FEVR; Fz-4; Fz4; FZD4S; FzE4; GPCR; hFz4
Target:    FZD4
UNIPROT ID:    Q9ULV1
描述:    Human FZD4 full length protein-synthetic nanodisc
背景:     A member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.
Species/Host:    HEK293
Molecular Weight:    The human full length FZD4 protein has a MW of 60.3 kDa
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure1. Elisa plates were pre-coated with Flag Tag FZD4-Nanodisc (0.2 µg/per well). Serial diluted Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for Flag monoclonal antibody binding with FZD4-Nanodisc is 1.843ng/ml.

Figure2. Human FZD4-Nanodisc, Flag Tag on SDS-PAGE
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