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FGFR1(P252S)

Anti-FGFR1(P252S) Mouse Monoclonal Antibody
5/5

¥4,800.00

货号：26254

规格： 100 微升

库存状态：In Stock

           产品描述          
产品名称:   FGFR1(P252S) 小鼠单抗
货号:   26254
基因符号:   FGFR1, BFGFR, CD331, CEK, FGFBR, FLG
描述:   FGFR1(P252S) 小鼠单抗
背景:   The protein FGFR1 is highly conserved between members and throughout evolution. This particular family member of FGFR1 binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations of FGFR1 protein have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, squamous cell lung cancer and autosomal dominant Kallmann syndrome.
免疫原 :   A synthetic peptide from the internal region of FGFR1 which includes the mutation of P252S, human origin.
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   
ELISA: 1:1000-1:2000
WB: 1:500-1:1000
IHC: 1:50-1:100
Concentration:   1 mg/ml
种属反应性:   Mouse
形式:   Liquid
克隆性：  Monoclonal
亚型:   IgG
纯化:   Purified from ascites
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
种属反应性:   Recognizes P252S mutant, but not wild type FGFR1 of vertebrates.
储存条件:    Store at -20°C. Avoid repeated freezing and thawing

蛋白质印迹:   

Western blot analysis of recombinant FGFR1(P252S) and wild type proteins.

Purified His-tagged FGFR1(P252S) protein (22-376aa, 45KD, lane 2) and corresponding wild type protein (lane 1) were blotted with Anti-FGFR1(P252S) monoclonal antibody (货号:26254).

Immunofluorescence:   

Immunofluorescence of cells expressing FGFR1 proteins with Anti-FGFR1(P252S) antibody.

HEK293T cells were transfected with pCDNA3-GFP-FGFR1(P252S) plasmid, pCDNA3-GFP-FGFR1 (WT) plasmid, pCDNA3-GFP-FGFR1 (P252R) plasmid or pCDNA3-GFP-FGFR1 (P252T) plasmid, then fixed and stained with Anti-FGFR1(P252S) monoclonal antibody (货号:26254).

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