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ERBB2(D769H)

Anti-ERBB2(D769H) Mouse Monoclonal Antibody
5/5

¥4,800.00

货号:26381

规格: 100 微升

库存状态:In Stock

           产品描述          
产品名称:   ERBB2(D769H) 小鼠单抗
货号:   货号::  26381
基因符号:  ERBB2/HER2/Neu/c-Neu
描述:   Anti-ERBB2(D769H) 小鼠单抗
背景:   The HER-2/neu oncogene, a member of the epidermal growth factor receptor or erb-B gene-like family, encodes a transmembrane tyrosine kinase receptor that mediates extracellular signals activated by epidermal growth factors. Her2 abnormal has been strongly associated with many malignant tumors, especially with breast cancers. The expression level of Her2 is an important criteria in clinic evaluating of the progression of breast cancer.
Immunogen:   A synthetic peptide from the internal region of ERBB2 which includes the mutation of D769H, human origin.
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   ELISA: 1:1000-1:2000WB: 1:500-1:1000IF: 1:25-1:50
Concentration:   1 mg/ml
种属反应性:   Mouse
形式:   Liquid
克隆性:   Monoclonal
亚型:   IgG
纯化:   Purified from ascites
Preservative: No
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
种属反应性:  Recognizes D769H mutant, but not wild type ERBB2 of vertebrates.
储存条件:      Store at -20°C. Avoid repeated freezing and thawing
蛋白质印迹:  Western blot analysis of recombinant ERBB2(D769H) and wild type proteins.Purified His-tagged ERBB2(D769H) protein (lane 1) and corresponding wild type protein (lane 2) were blotted with Anti-ERBB2(D769H) monoclonal antibody (货号:26381).Immunofluorescence:  Immunofluorescence of cells expressing ERBB2 proteins with Anti-ERBB2(D769H) antibody.HEK293T cells were transfected with pCDNA3-GFP-ERBB2 (WT) plasmid (left column) or pCDNA3-GFP-ERBB2(D769H) plasmid (right column), then fixed and stained with Anti-ERBB2(D769H) monoclonal antibody (货号:26381).
           引用文献