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EPCAM (DM147) Rabbit mAb

Anti-EPCAM (DM147) Rabbit Monoclonal Antibody
5/5

¥445.00

货号:28491

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   28491
产品全名:   EPCAM(DM147) 兔单克隆抗体
基因符号   EPCAM;TACSTD1;TROP1;CD326;DIAR5;EGP2;EGP314;EGP40;ESA;GA733-2;HNPCC8;HNPCC-8;KS1:4;KSA;M4S1;MIC18;MK1
描述:   EPCAM antibody(DM147) 兔单克隆抗体
背景:   This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.
经过测试的应用:   ELISA; Flow Cyt
推荐稀释比:   ELISA 1:5000-10000; Flow Cyt 1:100
种属反应性:   Rabbit
亚型:   Rabbit IgG
纯化:   Purified from cell culture supernatant by affinity chromatography
种属反应性:   人 EPCAM
成分:   Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. ELISA plate pre-coated by 1 µg/ml (100 µl/well) Human EPCAM protein, His tagged protein 11191 can bind Rabbit anti-EPCAM monoclonal antibody (clone: DM147) in a linear range of 5-100 ng/ml.

Figure 2. EPCAM protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-EPCAM (DM147) on Expi293 cells transfected with human EPCAM (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and  Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).
           引用文献