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Human CCR6 Full Length Protein

Human CCR6 Full Length Protein-Synthetic Nanodisc
5/5

$4,400.00

Cat.#:  11040

   Size:   50 μg

In Stock

          Product Description          
Cat.#:     11040
Product Name:   Human CCR6 Full Length Protein
规格:    10 µg, 50 µg and 100 µg
Synonyms:   BN-1; C-C CKR-6; CC-CKR-6; CCR-6; CD196; CKR-L3; CKRL3; CMKBR6; DCR2; DRY6; GPR29; GPRCY4; STRL22
Target:    CCR6
UNIPROT ID:    P51684
描述:    Human CCR6 full length protein-synthetic nanodisc
背景:     The protein is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene.
Species/Host:    HEK293
Molecular Weight:    The human full length CCR6 protein has a MW of 42.5 kDa
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure1. Elisa plates were pre-coated with Flag Tag CCR6-Nanodisc (0.2 µg/per well). Serial diluted Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for Flag monoclonal antibody binding with CCR6-Nanodisc is 2.691ng/ml.

Figure2. Human CCR6-Nanodisc, Flag Tag on SDS-PAGE
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