武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

邮箱:2716620741@qq.com

咨询:027 – 63497286 

BAFF-R (DM143) Rabbit mAb

Anti-BAFF-R (DM143) Rabbit Monoclonal Antibody
5/5

¥445.00

货号:28487

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   28487
产品全名:   BAFF-R(DM143) 兔单克隆抗体
基因符号   BAFFR;TNFRSF13C;BAFF-R;BROMIX;CD268;CVID4;prolixin
描述:   BAFF-R antibody(DM143) 兔单克隆抗体
背景:   B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also; some SLE patients have increased levels of BAFF in serum. Therefore; it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
经过测试的应用:   ELISA; Flow Cyt
推荐稀释比:   ELISA 1:5000-10000; Flow Cyt 1:100
种属反应性:   Rabbit
亚型:   Rabbit IgG
纯化:   Purified from cell culture supernatant by affinity chromatography
种属反应性:   人 BAFF-R
成分:   Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. ELISA plate pre-coated by 1 µg/ml (100 µl/well) Human BAFFR protein, mFc tagged protein 11170 can bind Rabbit anti-BAFFR monoclonal antibody (clone: DM143) in a linear range of 0.8-50

Figure 2. Flow cytometry analysis with Anti-BAFFR (DM143) on Expi293 cells transfected with human BAFFR (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
           引用文献