| 货号: S218247 |
| 产品全名: ZNF354A 兔多抗 |
| 基因符号 EZNF; HKL1; KID1; KID-1; TCF17; HEL104 |
| UNIPROT ID: O60765 (Gene Accession – BC047105 ) |
| 背景: ZNF354A, also called EZNF, KID-1 or TCF17, belongs to the Krppel C2H2-type zinc-finger family of proteins that contain KRAB domains and act as transcriptional regulators. Expressed primarily in the adult kidney, ZNF354A is a transcriptional repressor that plays a role in late renal development and is suppressed after renal ischemia. The N-terminus of ZNF354A contains the KRAB domain which confers transcriptional repressor activity, while the C-terminus contains multiple Cys2His2-zinc fingers. ZNF354A is located in the nucleolus and is thought to specifically influence development of the proximal tubule by shutting off dispensable or inhibitory genes. Reduced ZNF354A expression prevents proper cell differentiation and may, therefore, be implicated in renal carcinoma. |
| 抗原: Fusion protein of human ZNF354A |
| 经过测试的应用: ELISA, IHC |
| 推荐稀释比: IHC: 30-150; ELISA: 5000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse, Rat |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Epigenetics and Nuclear Signaling |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 218247(ZNF354A Antibody) at a dilution of 1/40(Nucleus and Cytoplasm). | 
In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the fusion protein and then with 218247(Anti-ZNF354A Antibody) at dilution 1/40. | 
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 218247(Anti-ZNF354A Antibody) at a dilution of 1/40. | 
In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with fusion protein and then with D224025(Anti-ZNF354A Antibody) at dilution 1/40. |
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