武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处
武汉费斯德生物科技有限公司是美国NewEast Biosciences在中国的办事处。NewEast Biosciences 在十二年前率先研发俩种独特的抗体。这俩种抗体仅仅识别活性的GTP酶或者突变的Oncogene。 GTP酶涉及(1)响应细胞表面受体激活的信号转导,包括跨膜受体,例如介导味觉、嗅觉和视觉的那些,(2)核糖体的蛋白质生物合成,(3)调节细胞分化、增殖、分裂和运动,(4)蛋白质通过膜的易位,(5)细胞内囊泡的运输,以及囊泡介导的分泌和摄取,通过GTP酶控制囊泡外壳组装。Oncogene侧是诱发癌症的基因。
我公司将向你提供以下的独一无二的三种抗体或者试剂盒: (1) 仅识别 GTP酶的活性构型的产品, 它可以让你能够量化GTP酶在细胞中的活性和分布。(2) 识别突变 Oncogene蛋白, 但不认识相应野生型的抗体。 (3) 对 cAMP 和 cGMP 具有超亲和力(无需乙酰化)ELISA检测试剂盒。这些产品被将近一千篇同行评议的文章所引用。
¥2,850.00
货号: N263093 | ||
产品全名: YAP1 兔单克隆抗体 | ||
基因符号 YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65 | ||
UNIPROT ID: P46937 | ||
背景: YAP (Yes-associated protein, YAP65) was identified based on its ability to associate with the SH3 domain of Yes. Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. | ||
抗原: A synthetic peptide of human YAP1 | ||
经过测试的应用: WB,IHC-P,IP | ||
推荐稀释比: WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20 | ||
种属反应性: Rabbit | ||
克隆性: Rabbit Monoclonal | ||
克隆编号: R06-6H7 | ||
分子量: Calculated MW: 54 kDa; Observed MW: 65 kDa | ||
亚型: IgG | ||
纯化: Affinity Purified | ||
种属反应性: Human | ||
成分: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||
研究领域: Signal Transduction | ||
储存和运输: Store at -20°C. Avoid repeated freezing and thawing | ||
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