| 货号: N225025 |
| 产品全名: Ubiquitin Conjugating Enzyme E2 A/B 兔多抗 |
| 基因符号 UBE2A; RAD6A; Ubiquitin-conjugating enzyme E2 A; RAD6 homolog A; HR6A; hHR6A; Ubiquitin carrier protein A; Ubiquitin-protein ligase A; UBE2B; RAD6B; Ubiquitin-conjugating enzyme E2 B; RAD6 homolog B; HR6B; hHR6B; Ubiquitin carrier protein B; Ubiquitin-conjugating enzyme E2-17 kDa; Ubiquitin-protein ligase B |
| UNIPROT ID: P49459/P63146 |
| 背景: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at ‘Lys-120’ to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. |
| 抗原: Synthesized peptide derived from the C-terminal region of human UBE2A/B. |
| 经过测试的应用: WB,IHC-P,ELISA |
| 推荐稀释比: WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 分子量: Calculated MW: 17 kDa; Observed MW: 17 kDa |
| 亚型: IgG |
| 纯化: Affinity Purified |
| 种属反应性: Human, Mouse and Rat |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
| 研究领域: Epigenetics and Nuclear Signaling |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin-embedded rat brain using Ubiquitin Conjugating Enzyme E2 A/B antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. | 
Western blot analysis of Ubiquitin Conjugating Enzyme E2 A/B in Jurkat lysates using UBE2A/B antibody. | 
Immunohistochemistry analysis of paraffin-embedded rat brain using Ubiquitin Conjugating Enzyme E2 A/B antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. | 
Immunohistochemistry analysis of paraffin-embedded mouse brain using Ubiquitin Conjugating Enzyme E2 A/B antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. |
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