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TNFSF10 Rabbit pAb

Anti-TNFSF10 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S216856

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S216856
产品全名:   TNFSF10 兔多抗
基因符号   TL2; APO2L; CD253; TRAIL; Apo-2L; TNLG6A
UNIPROT ID:   P50591 (Gene Accession – BC032722 )
背景:   The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
抗原:   Fusion protein of human TNFSF10
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 25-100; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Cancer, Cardiovascular
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human liver cancer tissue using 216856(TNFSF10 Antibody) at a dilution of 1/20(Cytoplasm and Cell membrane).
           引用文献