| 货号: N262936 |
| 产品全名: SSX2IP 兔单克隆抗体 |
| 基因符号 ADIP; hMsd1 |
| UNIPROT ID: Q9Y2D8 |
| 背景: Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin . Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via activation of Rac signaling . Acts as a centrosome maturation factor, probably by maintaining the integrity of the pericentriolar material and proper microtubule nucleation at mitotic spindle poles. The function seems to implicate at least in part WRAP73; the SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome (PubMed:23816619, PubMed:26545777). Involved in ciliogenesis (PubMed:24356449). It is required for targeted recruitment of the BBSome, CEP290, RAB8, and SSTR3 to the cilia (PubMed:24356449). |
| 抗原: A synthetic peptide of human SSX2IP |
| 经过测试的应用: WB,IHC-F,IHC-P,ICC/IF |
| 推荐稀释比: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Monoclonal |
| 克隆编号: R02-5B6 |
| 分子量: Calculated MW: 71 kDa; Observed MW: 71 kDa |
| 亚型: IgG |
| 纯化: Affinity Purified |
| 种属反应性: Human,Rat |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
| 研究领域: Tags & Cell Markers |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Western blot analysis of SSX2IP in Jurkat, Hela lysates using SSX2IP antibody | 
Immunocytochemistry analysis of SSX2IP (green) in K562 using SSX2IP antibody,and DAPI(blue). | 
Western blot analysis of SSX2IP in rat kidney lysates using SSX2IP antibody. | 
Immunohistochemistry analysis of paraffin-embedded Human Brain using SSX2IP antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. |
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