武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

邮箱:2716620741@qq.com

咨询:027 – 63497286 

SOCS1 Rabbit pAb

Anti-SOCS1 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:N225405

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N225405
产品全名:   SOCS1 兔多抗
基因符号   SOCS1; SSI1; TIP3; Suppressor of cytokine signaling 1; SOCS-1; JAK-binding protein; JAB; STAT-induced STAT inhibitor 1; SSI-1; Tec-interacting protein 3; TIP-3
UNIPROT ID:   O15524
背景:   This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.
抗原:   The antiserum was produced against synthesized peptide derived from human SOCS-1. AA range:49-98
经过测试的应用:   ICC/IF,WB,IHC-F,IHC-P,ELISA
推荐稀释比:   WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
分子量:   Calculated MW: 24 kDa; Observed MW: 38 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human, Mouse and Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Signal Transduction
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of SOCS1 in Jurkat lysates using SOCS1 antibody.
           引用文献