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SNAI1 Rabbit pAb

Anti-SNAI1 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:N225404

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N225404
产品全名:   SNAI1 兔多抗
基因符号   SNAH; Zinc finger protein SNAI1; Protein snail homolog 1; Protein sna
UNIPROT ID:   O95863
背景:   Snail is a zinc-finger transcription factor that can repress E-cadherin transcription. Downregulation of E-cadherin is associated with epithelial-mesenchymal transition during embryonic development, a process also exploited by invasive cancer cells . Indeed, loss of E-cadherin expression is correlated with the invasive properties of some tumors and there is a considerable inverse correlation between Snail and E-cadherin mRNA levels in epithelial tumor cell lines . In addition, Snail blocks the cell cycle and confers resistance to cell death . Phosphorylation of Snail by GSK-3 and PAK1 regulates its stability, cellular localization and function .Tissue specificity: Expressed in a variety of tissues with the highest expression in kidney.
抗原:   The antiserum was produced against synthesized peptide derived from human SNAI1. AA range:215-264
经过测试的应用:   WB,IHC-P,ICC/IF,ELISA
推荐稀释比:   WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
分子量:   Calculated MW: 29 kDa; Observed MW: 29 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human,Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of SNAI1 in 3T3 lysates using SNAI1 antibody.
           引用文献