武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

邮箱:2716620741@qq.com

咨询:027 – 63497286 

SLFN5 Rabbit pAb

Anti-SLFN5 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S218647

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S218647
产品全名:   SLFN5 兔多抗
基因符号   
UNIPROT ID:   Q08AF3 (Gene Accession – BC021238 )
背景:   Slfn5 (schlafen family member 5) is an 891 amino acid protein that exists as multiple alternatively spliced isoforms and is thought to play a role in hematopoeitic cell differentiation. The gene encoding Slfn5 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
抗原:   Fusion protein of human SLFN5
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 25-100; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Cancer
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 218647(SLFN5 Antibody) at a dilution of 1/20(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 218647(Anti-SLFN5 Antibody) at dilution 1/20.
           引用文献