| 货号: S222294 |
| 产品全名: RBFOX1 兔多抗 |
| 基因符号 2BP1; FOX1; A2BP1; FOX-1; HRNBP1 |
| UNIPROT ID: Q9NWB1 (Gene Accession – NP_001135805 ) |
| 背景: The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| 抗原: Synthetic peptide of human RBFOX1 |
| 经过测试的应用: ELISA, IHC |
| 推荐稀释比: IHC: 40-200; ELISA: 5000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Epigenetics and Nuclear Signaling, Neuroscience, Developmental Biology |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 222294(RBFOX1 Antibody) at a dilution of 1/40(Cytoplasm). | 
In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 222294(Anti-RBFOX1 Antibody) at dilution 1/40. | 
The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 222294(Anti-RBFOX1 Antibody) at a dilution of 1/40. | 
In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with synthetic peptide and then with D264346(Anti-RBFOX1 Antibody) at dilution 1/40. |
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