武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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RAE1 Rabbit pAb

Anti-RAE1 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S217735

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S217735
产品全名:   RAE1 兔多抗
基因符号   Gle2; MIG14; MRNP41; Mnrp41; dJ481F12.3; dJ800J21.1
UNIPROT ID:   P78406 (Gene Accession – BC106923 )
背景:   Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
抗原:   Fusion protein of human RAE1
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 200-400; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction, Epigenetics and Nuclear Signaling, Cancer
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human ovarian cancer tissue using 217735(RAE1 Antibody) at a dilution of 1/220(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with the fusion protein and then with 217735(Anti-RAE1 Antibody) at dilution 1/220.
           引用文献