| 货号: S214603 |
| 产品全名: PTPN12 兔多抗 |
| 基因符号 PTPG1; PTP-PEST |
| UNIPROT ID: Q05209 (Gene Accession – NP_001124480 ) |
| 背景: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. |
| 抗原: Synthetic peptide of human PTPN12 |
| 经过测试的应用: ELISA, WB, IHC |
| 推荐稀释比: IHC: 100-300;WB: 200-1000;ELISA: 1000-2000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Signal Transduction |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 214603(PTPN12 Antibody) at a dilution of 1/45(Cytoplasm). | 
In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the synthetic peptide and then with 214603(Anti-PTPN12 Antibody) at dilution 1/45. | 
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 214603(Anti-PTPN12 Antibody) at a dilution of 1/45. | 
In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with synthetic peptide and then with D162089(Anti-PTPN12 Antibody) at dilution 1/45. | 
Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: 231 cells, K562 cells;
Primary antibody: 214603(PTPN12 Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 10 minutes | |
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