武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处
武汉费斯德生物科技有限公司是美国NewEast Biosciences在中国的办事处。NewEast Biosciences 在十二年前率先研发俩种独特的抗体。这俩种抗体仅仅识别活性的GTP酶或者突变的Oncogene。 GTP酶涉及(1)响应细胞表面受体激活的信号转导,包括跨膜受体,例如介导味觉、嗅觉和视觉的那些,(2)核糖体的蛋白质生物合成,(3)调节细胞分化、增殖、分裂和运动,(4)蛋白质通过膜的易位,(5)细胞内囊泡的运输,以及囊泡介导的分泌和摄取,通过GTP酶控制囊泡外壳组装。Oncogene侧是诱发癌症的基因。
我公司将向你提供以下的独一无二的三种抗体或者试剂盒: (1) 仅识别 GTP酶的活性构型的产品, 它可以让你能够量化GTP酶在细胞中的活性和分布。(2) 识别突变 Oncogene蛋白, 但不认识相应野生型的抗体。 (3) 对 cAMP 和 cGMP 具有超亲和力(无需乙酰化)ELISA检测试剂盒。这些产品被将近一千篇同行评议的文章所引用。
¥2,850.00
货号: N261322 |
产品全名: Phospho-STAT3 (Tyr705) (5E9) 小鼠单抗 |
基因符号 STAT3; APRF; Signal transducer and activator of transcription 3; Acute-phase response factor |
UNIPROT ID: P40763 |
背景: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. |
抗原: Synthetic peptide conjugated to KLH. |
经过测试的应用: IHC-P |
推荐稀释比: IHC: 1/50-1/100 |
种属反应性: Mouse |
克隆性: Mouse Monoclonal |
克隆编号: 5E9-4D2-10H7 |
分子量: – |
亚型: IgG1 |
纯化: Affinity Purified |
种属反应性: Human |
Modification: Phosphorylated |
成分: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
研究领域: Signal Transduction |
储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin-embedded Human Breast Carcinoma Tissue using Phospho-STAT3 (Tyr705) (5E9) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. |