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Phospho-p107 (Thr369) Rabbit pAb

Anti-Phospho-p107 (Thr369) Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:N225488

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N225488
产品全名:   Phospho-p107 (Thr369) 兔多抗
基因符号   PRB1; p107; CP107
UNIPROT ID:   P28749
背景:   Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 ‘Lys-20’ trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation. Forms a complex with adenovirus E1A and with SV40 large T antigen. May bind and modulate functionally certain cellular proteins with which T and E1A compete for pocket binding. May act as a tumor suppressor.
抗原:   The antiserum was produced against synthesized peptide derived from human RBL1 around the phosphorylation site of Thr369. AA range:335-384
经过测试的应用:   IHC-P,ELISA
推荐稀释比:   IHC: 1/50-1/100 ELISA: 1/10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
分子量:   
亚型:   IgG
纯化:   Affinity Chromatography
种属反应性:   Human,Mouse
Modification:   Phosphorylated
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Cell Biology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemical analysis of paraffin-embedded Human tonsils using Phospho-p107 (Thr369) antibody. Sample with blocking peptide on the right.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

EnzymeLinked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phospho-peptide (Phospho-left) and NonPhospho-peptide (Phospho-right), using RBL1 (Phospho-Thr36antibody
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