武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处
武汉费斯德生物科技有限公司是美国NewEast Biosciences在中国的办事处。NewEast Biosciences 在十二年前率先研发俩种独特的抗体。这俩种抗体仅仅识别活性的GTP酶或者突变的Oncogene。 GTP酶涉及(1)响应细胞表面受体激活的信号转导,包括跨膜受体,例如介导味觉、嗅觉和视觉的那些,(2)核糖体的蛋白质生物合成,(3)调节细胞分化、增殖、分裂和运动,(4)蛋白质通过膜的易位,(5)细胞内囊泡的运输,以及囊泡介导的分泌和摄取,通过GTP酶控制囊泡外壳组装。Oncogene侧是诱发癌症的基因。
我公司将向你提供以下的独一无二的三种抗体或者试剂盒: (1) 仅识别 GTP酶的活性构型的产品, 它可以让你能够量化GTP酶在细胞中的活性和分布。(2) 识别突变 Oncogene蛋白, 但不认识相应野生型的抗体。 (3) 对 cAMP 和 cGMP 具有超亲和力(无需乙酰化)ELISA检测试剂盒。这些产品被将近一千篇同行评议的文章所引用。
¥2,850.00
货号: N263157 | ||||
产品全名: Phospho-delta 1 Catenin (Thr916) 兔单克隆抗体 | ||||
基因符号 CAS; p120; BCDS2; CTNND; P120CAS; P120CTN; p120(CAS); p120(CTN) | ||||
UNIPROT ID: O60716 | ||||
背景: Catenin δ-1 (p120 catenin) has an amino-terminal coiled-coil domain followed by a regulatory domain containing multiple phosphorylation sites and a central Armadillo repeat domain of ten linked 42-amino acid repeats. The carboxy-terminal tail has no known function. Catenin δ-1 fulfills critical roles in the regulation of cell-cell adhesion as it regulates E-cadherin turnover at the cell surface to determine the level of E-cadherin available for cell-cell adhesion. | ||||
抗原: A synthetic phosphopeptide corresponding to residues surrounding Thr916 of human delta 1 Catenin/CAS | ||||
经过测试的应用: WB,IHC-F,IHC-P,ICC/IF | ||||
推荐稀释比: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 | ||||
种属反应性: Rabbit | ||||
克隆性: Rabbit Monoclonal | ||||
克隆编号: R07-5A6 | ||||
分子量: Calculated MW: 108 kDa; Observed MW: 100 kDa | ||||
亚型: IgG | ||||
纯化: Affinity Purified | ||||
种属反应性: Human,Mouse | ||||
Modification: Phosphorylated | ||||
成分: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||||
研究领域: Cell Biology | ||||
储存和运输: Store at -20°C. Avoid repeated freezing and thawing | ||||
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