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Phospho-4E BP1 (Thr46) Rabbit mAb

Anti-Phospho-4E BP1 (Thr46) Rabbit Monoclonal Antibody
5/5

¥2,850.00

货号:N261722

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N261722
产品全名:   Phospho-4E BP1 (Thr46) 兔单克隆抗体
基因符号   EIF4EBP1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I
UNIPROT ID:   Q13541
背景:   Translation repressor protein 4E-BP1 (also known as PHAS-1) inhibits cap-dependent translation by binding to the translation initiation factor eIF4E. Hyperphosphorylation of 4E-BP1 disrupts this interaction and results in activation of cap-dependent translation. Both the PI3 kinase/Akt pathway and FRAP/mTOR kinase regulate 4E-BP1 activity.
抗原:   A synthetic phosphopeptide corresponding to residues surrounding Thr45 of human eIF4EBP1
经过测试的应用:   WB,IHC-P,IP
推荐稀释比:   WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
种属反应性:   Rabbit
克隆性:   Rabbit Monoclonal
克隆编号:   R03-5C7
分子量:   Calculated MW: 13 kDa; Observed MW: 15-20 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human, Mouse and Rat
Modification:   Phosphorylated
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human breast cancer using eIF4EBP1/eIF4EBP2/eIF4EBP3 (Phospho- T45) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of Phospho-eIF4EBP1 (Thr46) in K562, C6, 3T3, Hela lysates using Phospho-4E BP1 (Thr46) antibody.
           引用文献