武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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PCSK5 Rabbit pAb

Anti-PCSK5 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S218924

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S218924
产品全名:   PCSK5 兔多抗
基因符号   PC5; PC6; PC6A; SPC6
UNIPROT ID:   Q92824 (Gene Accession – BC012064 )
背景:   This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER. It then sorts to the trans-Golgi network where a second autocatalytic event takes place and the catalytic activity is acquired. This encoded protein is widely expressed and one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It mediates posttranslational endoproteolytic processing for several integrin alpha subunits and is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Alternative splicing results in multiple transcript variants, some of which encode distinct isoforms, including a protease packaged into dense core granules (PC5A) and a type 1 membrane bound protease (PC5B).
抗原:   Fusion protein of human PCSK5
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 30-150; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling, Cell Biology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 218924(PCSK5 Antibody) at a dilution of 1/35(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the fusion protein and then with 218924(Anti-PCSK5 Antibody) at dilution 1/35.
           引用文献