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p300 Rabbit pAb

Anti-p300 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:N225478

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N225478
产品全名:   p300 兔多抗
基因符号   EP300; P300; Histone acetyltransferase p300; p300 HAT; E1A-associated protein p300
UNIPROT ID:   Q09472
背景:   EP300: E1A binding protein p300. This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.
抗原:   Synthesized peptide derived from the Internal region of human p300.
经过测试的应用:   ICC/IF,WB,IHC-F,IHC-P,ELISA
推荐稀释比:   WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
分子量:   Calculated MW: 264 kDa; Observed MW: 300 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human, Mouse and Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Hypoxia Signal Transduction& Hypoxia-induced
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human breastcancer using p300 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of p300 in HELA, 293T, 823AV lysates using p300 antibody.
           引用文献