武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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NTH1 Rabbit mAb

Anti-NTH1 Rabbit Monoclonal Antibody
5/5

¥2,850.00

货号:N262626

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N262626
产品全名:   NTH1 兔单克隆抗体
基因符号   FAP3; NTH1; OCTS3; hNTH1
UNIPROT ID:   P78549
背景:   Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP-lyase activity cleaves the phosphodiester bond 3′ to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. Has also 8-oxo-7,8-dihydroguanine (8-oxoG) DNA glycosylase activity. Acts preferentially on DNA damage opposite guanine residues in DNA. Is able to process lesions in nucleosomes without requiring or inducing nucleosome disruption.
抗原:   Recombinant protein of human NTH1
经过测试的应用:   WB,ICC/IF
推荐稀释比:   WB: 1/500-1/1000 IF: 1/50-1/200
种属反应性:   Rabbit
克隆性:   Rabbit Monoclonal
克隆编号:   R08-8E9
分子量:   Calculated MW: 34 kDa; Observed MW: 34 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of NTH1 in K562, Hela lysates using NTH1 antibody.

Immunocytochemistry analysis of NTH1 (green) in Hela using NTH1 antibody,and DAPI(blue).
           引用文献