| 货号: S216288 |
| 产品全名: NFKBID 兔多抗 |
| 基因符号 TA-NFKBH, IkappaBNS |
| UNIPROT ID: Q8NI38 (Gene Accession – BC006273 ) |
| 背景: May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR-induced negative selection of thymocytes.I?BNS, the nuclear I?B-like protein encoded by Nfkbid, is required for the development of marginal zone and peritoneal B-1 B cells and additionally required for extrafollicular antibody responses to T-independent and -dependent immunogens.I?BNS has been identified as a member of the I?B family of NF-κB inhibitors, which undergoes induction upon TCR signaling. I?BNS mediates both positive and negative gene regulation, depending on individual cell type and/or cytokine. |
| 抗原: Fusion protein of human NFKBID |
| 经过测试的应用: ELISA, WB, IHC |
| 推荐稀释比: IHC: 25-100;WB: 200-1000;ELISA: 1000-5000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Signal Transduction, Epigenetics and Nuclear Signaling, Immunology |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human colon cancer tissue using 216288(NFKBID Antibody) at a dilution of 1/40(Cytoplasm, Nucleus). | 
In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with the fusion protein and then with 216288(Anti-NFKBID Antibody) at dilution 1/40. | 
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 216288(Anti-NFKBID Antibody) at a dilution of 1/40. | 
In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with fusion protein and then with D220139(Anti-NFKBID Antibody) at dilution 1/40. | 
Gel: 10+12%SDS-PAGE, Lysate: 40 μg;
Lane: RAW264.7 cells;
Primary antibody: 216288(NFKBID Antibody) at dilution 1/650;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 2 minutes | |
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