| 货号: S219922 |
| 产品全名: MMP11 兔多抗 |
| 基因符号 ST3, SL-3, STMY3 |
| UNIPROT ID: P24347 (Gene Accession – AAH57788 ) |
| 背景: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP’s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP’s, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. |
| 抗原: Synthetic peptide of human MMP11 |
| 经过测试的应用: ELISA, WB, IHC |
| 推荐稀释比: IHC: 50-200;WB: 500-2000;ELISA: 1000-5000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Signal Transduction, Cardiovascular, Cell Biology |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 219922(MMP11 Antibody) at a dilution of 1/40(Cytoplasm, ExtraCellular matrix). | 
In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the synthetic peptide and then with 219922(Anti-MMP11 Antibody) at dilution 1/40. | 
The image on the left is immunohistochemistry of paraffin-embedded Human renal cancer tissue using 219922(Anti-MMP11 Antibody) at a dilution of 1/40. | 
In comparision with the IHC on the left, the same paraffin-embedded Human renal cancer tissue is first treated with synthetic peptide and then with D260628(Anti-MMP11 Antibody) at dilution 1/40. | 
Gel: 10%SDS-PAGE, Lysate: 60 μg;
Lane 1-2: Human colon tissue, Human ovarian cancer tissue;
Primary antibody: 219922(MMP11 Antibody) at dilution 1/600;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 1 minute | |
|
