| 货号: S216823 |
| 产品全名: MAP3K9 兔多抗 |
| 基因符号 MLK1; MEKK9; PRKE1 |
| UNIPROT ID: P80192 (Gene Accession – BC133706 ) |
| 背景: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis. |
| 抗原: Fusion protein of human MAP3K9 |
| 经过测试的应用: ELISA, IHC |
| 推荐稀释比: IHC: 100-200; ELISA: 5000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Apoptosis, Signal Transduction |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human gastric cancer tissue using 216823(MAP3K9 Antibody) at a dilution of 1/120(Cytoplasm). | 
In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with the fusion protein and then with 216823(Anti-MAP3K9 Antibody) at dilution 1/120. | 
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 216823(Anti-MAP3K9 Antibody) at a dilution of 1/120. | 
In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with fusion protein and then with D221304(Anti-MAP3K9 Antibody) at dilution 1/120. |
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