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LEPR(S/L) Rabbit pAb

Anti-LEPR(S/L) Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S219886

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S219886
产品全名:   LEPR(S/L) 兔多抗
基因符号   OBR; OB-R; CD295; LEP-R; LEPRD
UNIPROT ID:   P48357 (Gene Accession – NP_002294 )
背景:   The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).
抗原:   Synthetic peptide of human LEPR(S/L)
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 25-100; ELISA: 2000-5000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction, Cancer, Metabolism, Cardiovascular
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 219886(LEPR(S/L) Antibody) at a dilution of 1/25(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the synthetic peptide and then with 219886(Anti-LEPR(Anti-S/L) Antibody) at dilution 1/25.
           引用文献