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Lamin A/C (5D12) Mouse mAb

Anti-Lamin A/C (5D12) Mouse Monoclonal Antibody
5/5

¥2,850.00

货号:N261447

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N261447
产品全名:   Lamin A/C (5D12) 小鼠单抗
基因符号   LMNA; LMN1; Prelamin-A/C
UNIPROT ID:   P02545
背景:   Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Play an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics.Prelamin-A/C can accelerate smooth muscle cell senescence. It acts to disrupt mitosis and induce DNA damage in vascular smooth muscle cells (VSMCs), leading to mitotic failure, genomic instability, and premature senescence.
抗原:   Purified recombinant human LMNA protein fragments expressed in E.coli.
经过测试的应用:   WB,ICC/IF
推荐稀释比:   WB: 1/500-1/1000 IF: 1/50-1/200
种属反应性:   Mouse
克隆性:   Mouse Monoclonal
克隆编号:   5D12-C6-E9
分子量:   Calculated MW: 74 kDa; Observed MW: 63,74 kDa
亚型:   IgG1
纯化:   Affinity Purified
种属反应性:   Human, Mouse and Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Tags & Cell Markers
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunofluorescence analysis of Lamin A/C (5D12) in A549 using Lamin A/C antibody.

Western blot analysis of Lamin A/C in MCF-7, A549 and Hela lysates using Lamin A/C antibody.
           引用文献